Labdane Diterpenoids from Leonotis leonurus
نویسندگان
چکیده
منابع مشابه
Leonotis leonurus: A herbal medicine review
Leonotis leonurus (L.) R. Br. is a shrub widely known as wild dagga found in most parts of the world and belongs to the Lamiaceae family. Some of the many traditional applications of L. Leonurus include the leaf decoction being a strong purgative and used for wound healing and asthma. The leaves and stem are topically applied to sores and skin infections, or taken for high blood pressure and di...
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Three new labdane diterpenoids, calomacrins A-C (1-3), and a new diaryl butyrolactone-type lignan, calomacrol A (8), as well as four known labdane diterpenoids and six known lignans, were isolated from the twigs and leaves of Calocedrus macrolepis. Structures of the new compounds were elucidated on the basis of their spectroscopic methods, including 1D and 2D NMR techniques. Compounds 3-14 were...
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Seven new labdane-type diterpenoids, vitextrifolins A-G (1-7), along with eight previously reported analogues, were isolated from the fruits of Vitex trifolia. The structures of 1-7 were elucidated by spectroscopic data interpretation. The isolates were evaluated for their cytotoxicity against four human cancer cell lines (A549, HCT116, HL-60, and ZR-75-30), but all were inactive (IC(50) < 5 μg...
متن کاملTwo new labdane diterpenes from fresh leaves of Leonurus japonicus and their degradation during drying.
Degradation of the components of Leonurus Herb was examined during drying. Compounds 1 and 2 were detected on TLC at lower temperature, but not at higher temperature. Their chemical structures were determined by spectral methods. They immediately decomposed even at 40°C in chloroform solution. They are believed to be transformed through a retro-aldol reaction. Compounds 1 and 2 have not been pr...
متن کاملEffects of Leonotis leonurus aqueous extract on the isolated perfused rat heart
The use the aqueous decoction of Leonotis leonurus (L. leonurus) (Ll) R. Br. (Lamiaceae) in the treatment of hypertension (HPT) in traditional medicine is well documented. The effect of the aqueous extract of LI on the blood pressure (BP) and heart rate (HR) has been investigated in normotensive rats. The aim of this study was to investigate the effect of Ll aqueous extract on the in isolated p...
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ژورنال
عنوان ژورنال: Phytochemistry
سال: 2013
ISSN: 0031-9422
DOI: 10.1016/j.phytochem.2012.02.021